✦ LIBER ✦

Novel 17-Azolyl Steroids, Potent Inhibitors of Human Cytochrome 17α-Hydroxylase-C17,20-lyase (P45017α): Potential Agents for the Treatment of Prostate Cancer

✍ Scribed by Njar, Vincent C. O.; Kato, Katsuya; Nnane, Ivo P.; Grigoryev, Dmitry N.; Long, Brian J.; Brodie, Angela M. H.

Book ID: 111677145
Publisher: American Chemical Society
Year: 1998
Tongue: English
Weight: 174 KB
Volume: 41
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm970568r

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pharmacology of novel steroidal inhibito

Pharmacology of novel steroidal inhibitors of cytochrome P45017α (17α-hydroxylase/C17–20 lyase)

✍ Barrie, S.E.; Potter, G.A.; Goddard, P.M.; Haynes, B.P.; Dowsett, M.; Jarman, M. 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 592 KB

3- and 4-Pyridylalkyl Adamantanecarboxyl

3- and 4-Pyridylalkyl Adamantanecarboxylates: Inhibitors of Human Cytochrome P45017α (17α-Hydroxylase/C17,20-Lyase). Potential Nonsteroidal Agents for the Treatment of Prostatic Cancer

✍ Chan, Ferdinand C. Y.; Potter, Gerard A.; Barrie, S. Elaine; Haynes, Benjamin P. 📂 Article 📅 1996 🏛 American Chemical Society 🌐 English ⚖ 122 KB

ChemInform Abstract: Inhibitors of 17α-H

ChemInform Abstract: Inhibitors of 17α-Hydroxylase/17,20-Lyase (CYP17): Potential Agents for the Treatment of Prostate Cancer

✍ V. C. O. Njar; A. M. H. Brodie 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

17β-(Cyclopropylamino)-androst-5-en-3β-o

17β-(Cyclopropylamino)-androst-5-en-3β-ol, a selective mechanism-based inhibitor of cytochrome P45017α (steroid 17α-hydroxylase/C17–20 lyase)

✍ Michael R. Angelastro; Marie E. Laughlin; Gerald L. Schatzman; Philippe Bey; Tho 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 425 KB

17-Imidazolyl, Pyrazolyl, and Isoxazolyl

17-Imidazolyl, Pyrazolyl, and Isoxazolyl Androstene Derivatives. Novel Steroidal Inhibitors of Human Cytochrome Cl7,20-Lyase (P45017α)†

✍ Ling, Yang-zhi; Li, Ji-song; Liu, Yang; Kato, Katsuya; Klus, Gregory T.; Brodie, 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 196 KB

Novel nonsteroidal inhibitor of cytochro

Novel nonsteroidal inhibitor of cytochrome P45017α (17α-hydroxylase/C17–20 lyase), YM116, decreased prostatic weights by reducing serum concentrations of testosterone and adrenal androgens in rats

✍ Ideyama, Yukitaka; Kudoh, Masafumi; Tanimoto, Kyoko; Susaki, Yoko; Nanya, Taiki; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 257 KB

## Background: The purpose of this study was to determine the effects of a nonsteroidal c17-20 lyase inhibitor, 2-(1h-imidazol-4-ylmethyl)-9h-carbazole (ym116), on serum concentrations of androgens and ventral prostatic weight in rats. ## Methods: Serum concentrations of testosterone and of dehyd