Nouvelle synthèse et étude de la stabilité de l'amino-3 thiophène

✍ Scribed by S. Rault; M. Cugnon de Sevricourt; M. Robba

• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 405 KB
• Volume: 101
• Category: Article
• ISSN: 0165-0513
• DOI: 10.1002/recl.19821010604

✦ Synopsis

Abstract

A new synthesis of 3‐aminothiophene is proposed starting from 3‐thenoic acid via isopropyl 3‐thienylcarbamate as intermediate. Thermal decomposition of this latter in alkaline medium gives 3‐aminothiophene.

NMR and mass spectral studies revealed that the instability of the amine is due to its polymerisation via the formation of the dimer di‐3‐thienylamine and the trimer tri‐3‐thienylamine.