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Notochordal Cells Protect Nucleus Pulposus Cells from Apoptosis: Implications for the Mechanisms of Intervertebral Disc Degeneration

โœ Scribed by William Mark Erwin; Diana Islam; Robert Davies-Inman; Michael G. Fehlings; Florence W. Tsui

Book ID
119372668
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
48 KB
Volume
12
Category
Article
ISSN
1529-9430

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## Abstract Intervertebral disc degeneration (IDD) pertains to the loss of extracellular matrix (ECM), particularly the early loss of aggrecan, the turnover of which is regulated by ADAMTSs. Amongst the etiological factors of IDD, mechanical stress plays an important role in the physiological and p