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Hypoxia-inducible factor regulation of ANK expression in nucleus pulposus cells: Possible implications in controlling dystrophic mineralization in the intervertebral disc

✍ Scribed by Renata Skubutyte; Dessislava Markova; Theresa A. Freeman; D. Greg Anderson; Arnold S. Dion; Charlene J. Williams; Irving M. Shapiro; Makarand V. Risbud


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
252 KB
Volume
62
Category
Article
ISSN
0004-3591

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## Objective. To investigate transforming growth factor ␀ (TGF␀) regulation of CCN3 expression in cells of the nucleus pulposus. Methods. Real-time reverse transcriptionpolymerase chain reaction and Western blot analyses were used to measure CCN3 expression in the nucleus pulposus. Transfections w