Ring-cleavage of Phthalidisoquinoline Al
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Silvia von Angerer; Erwin von Angerer; Reinhard Ambros; Wolfgang Wiegrebe
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Article
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1992
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John Wiley and Sons
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English
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Degradation of (->a-narcotine (5). (-)-p-narcotine (6), and (-tP-hydrastine (7) with ethyl chloroformate (ECF) affords the chloro-urethans 9 and 18, respectively. Diastereomer 9-1 is easily hydrolyzed to the hydroxy-urethan 10, whilst 18 is converted to the methoxy-analogue 19. The stilbene lactone