✍ Scribed by N. Heyboer; G. Heymens Visser; K. E. T. Kerling
No coin nor oath required. For personal study only.
A study has been made of 2‐methyl‐1‐nitroisourea as a reagent for the conversion of amino groups of amino acids into guanidino groups. This reagent has proved its usefulness in modifying the ω‐amino groups of diaminocarboxylic acids in particular. The reaction of 2‐methyl‐1‐nitroisourea with glycine, L‐ornithine and D‐ and L‐lysine to yield nitroguanidinoacetic acid, L‐nitroarginine and D‐ and L‐nitrohomoarginine, respectively, is described.
📜 SIMILAR VOLUMES
Williams of Notre Dame, AMONG the numerous conformational equilibrium values reported in the literature 1,2 that of the amino group is conspicuously missing. Tich;, Jon;; and Sicher3 some years ago determined pK data which indicate a qualitatively that the -dG value for the equilibrium is comparable
VALUES for the free energy change involved in moving en equatorial subetltuent on a cyclohexene chair into the axial poeition (A-values') have, in the past several years, become