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Notch tumor suppressor function

✍ Scribed by Dotto, G P

Book ID: 109970548
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 266 KB
Volume: 27
Category: Article
ISSN: 0950-9232
DOI: 10.1038/onc.2008.225

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## Abstract The retinoblastoma sensitivity protein (Rb) and the p53 gene product both appear to function as negative regulators of cell division or abnormal cellular growth in some differentiated cell types. Several types of cancers have been shown to be derived from cells that have extensively mut