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Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein

✍ Scribed by Guo-Hui Li; Yu-Zhen Fan; Xiao-Wei Liu; Bing-Fang Zhang; Dan-Dan Yin; Fei He; Si-Yong Huang; Zhi-Jie Kang; Heng Xu; Qiang Liu; Yan-Lan Wu; Xiao-Li Niu; Li Zhang; Li Liu; Miao-Wang Hao; Hua Han; Ying-Min Liang

Book ID
106459131
Publisher
Springer
Year
2010
Tongue
English
Weight
348 KB
Volume
340
Category
Article
ISSN
0300-8177

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## Abstract We have begun to characterize the development of the excitation – response coupling sequence in the human promyelocytic leukemia cell line HL60. Using the recently developed fluorescent calcium probe quin‐2, it was found that DMSO induced myeloid differentiation of the HL60 cells is acc