An Artificial Protein with the Biological Activity of the Differentiation Factor for the HL-60 Cell Line of Human Promyelocyte Leukemia
β Scribed by R. V. Chertkova; I. A. Kostanyan; M. V. Astapova; E. A. Surina; D. A. Dolgikh; M. P. Kirpichnikov
- Book ID
- 110417919
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2003
- Tongue
- English
- Weight
- 130 KB
- Volume
- 29
- Category
- Article
- ISSN
- 1068-1620
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## Abstract We have begun to characterize the development of the excitation β response coupling sequence in the human promyelocytic leukemia cell line HL60. Using the recently developed fluorescent calcium probe quinβ2, it was found that DMSO induced myeloid differentiation of the HL60 cells is acc
The role of magnesium ions in the differentiation of human promyelocytic leukemia HL-60 cells was investigated. When HL-60 extracellular magnesium was deficient (less than 0.01 mM), the total intracellular magnesium content and [3H] leucine incorporation rates decreased to 61 and 28%, respectively,