Notch signaling during chondrogenesis of human bone marrow stem cells
β Scribed by Rachel A. Oldershaw; Tim E. Hardingham
- Book ID
- 116322416
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 797 KB
- Volume
- 46
- Category
- Article
- ISSN
- 8756-3282
No coin nor oath required. For personal study only.
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## Abstract Mesenchymal stem cells derived from human bone marrow (hBMβMSCs) can differentiate into chondrogenic cells for the potential treatment of injured articular cartilage. To evaluate agarose gels as a supportive material for chondrogenesis of hBMβMSCs, this study examined chondrogenesis of
## Abstract Two chondrogenic factors, Dex and TGFβ__Ξ²__1, were incorporated into PLGA scaffolds and their chondrogenic potential was evaluated. The Dexβloaded PLGA scaffold was grafted with AA and heparin, the heparinβimmobilized one was then reacted with TGFβ__Ξ²__1, yielding a PLGA/DexβTGF (PLGA/D