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Notch Signaling: Cell Fate Control and Signal Integration in Development

โœ Scribed by Artavanis-Tsakonas, S.


Book ID
118745541
Publisher
American Association for the Advancement of Science
Year
1999
Tongue
English
Weight
575 KB
Volume
284
Category
Article
ISSN
0036-8075

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cell lineage and may function together with signals from the pre-TCR and the TCR to regulate subsequent steps of T cell development.

Notch signaling in T- and B-cell develop
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The Notch family of evolutionarily conserved proteins regulates a broad spectrum of cell-fate decisions and differentiation processes during fetal and post-natal development. The best characterized role of Notch signaling during mammalian hematopoiesis and lymphopoiesis is the essential function of