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Notch Inhibits Expression of the Kruppel-Like Factor 4 Tumor Suppressor in the Intestinal Epithelium

✍ Scribed by Ghaleb, A. M.; Aggarwal, G.; Bialkowska, A. B.; Nandan, M. O.; Yang, V. W.


Book ID
125856445
Publisher
American Association for Cancer Research
Year
2008
Tongue
English
Weight
501 KB
Volume
6
Category
Article
ISSN
1541-7786

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Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide, reflecting incomplete characterization of underlying mechanisms and lack of early detection. Kru ¨ppel-like factor 6 (KLF6) is a ubiquitously expressed zinc finger transcription factor that is deregulated in multiple cancer