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Notch Activity Influences the αβ versus γδ T Cell Lineage Decision

✍ Scribed by Tracy Washburn; Edina Schweighoffer; Thomas Gridley; David Chang; B.J Fowlkes; Dragana Cado; Ellen Robey


Book ID
117268607
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
251 KB
Volume
88
Category
Article
ISSN
0092-8674

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During thymic development, immature T cells rearrange and express the genes encoding the T-cell antigen receptor and mature as either o~1~ or '{8 lineage T cells. In the past year, advances have been made in understanding the role of individual components of the T-cell antigen receptor complex in th