Normalp-complements and fixed elements
β Scribed by I. M. Isaacs; Gabriel Navarro
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 122 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0003-889X
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## Abstract Cytomegalovirus (CMV)βspecific IgM that fixes complement in the presence of CMV antigen was demonstrated in sera from five patients with primary CMV infection. The CF reaction, demonstrable in the IgM fractions of the sera, was not affected significantly by absorption with aggregated Ig
Cytomegalovirus-specific complement-fixing IgM (CMV CF-IgM) antibody was detected in 12/84 (14.3 percent) sera containing CMV-specific IgM. Higher titres were obtained by using a purified antigen preparation containing enveloped virus particles and membrane fragments when compared with a crude extra