## Abstract Magnetic resonance imaging (MRI) has been widely used to diagnose and monitor multiple sclerosis (MS). Although MRIβvisible lesions are a key feature of MS, they are thought to correlate poorly with clinical progression. Neurodegeneration is increasingly being recognized as an important
Normalized regional brain atrophy measurements in multiple sclerosis
β Scribed by Robert Zivadinov; Laura Locatelli; Barbara Stival; Alessio Bratina; Attilio Grop; Davide Nasuelli; Ozana Brnabic-Razmilic; Marino Zorzon
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 206 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0028-3940
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## Abstract ## Purpose To investigate intercenter agreement of brain volume (change) measurement in multiple sclerosis (MS) using structural image evaluation using normalization of atrophy (SIENA) and the crossβsectional version of SIENA (SIENAX) with additional manual editing to correct for inade
## Abstract ## Purpose To investigate whether multiple sclerosis (MS) atrophy can be assessed by SIENA and SIENAX software using other image types from MS research protocols than T1βweighted images without contrast agent, which are not always available. ## Materials and Methods We selected 46 MS