Normal serum immunoglobulins influence the numbers of bone marrow pre-B and B cells
✍ Scribed by Anne Sundblad; Miguel Marcos; Francois Huetz; António Freitas; Christoph Heusser; Denis Portnoi; António Coutinho
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 709 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## ABSTRACT Aim of the study was the establishment of a standardized in vitro culture system for studies on proliferation and differentiation of human leukemic pre ‐ B cells. Coincubation with human stromal cells led to a significantly higher proliferation of the cytokine ‐ sensitive leukemic pre ‐
## Abstract Immunofluorescent techniques were used to examine several aspects of B cell ontogeny in humans. Large lymphoid cells containing intracytoplasmic IgM (pre‐B cells) were present in fetal liver as early as 7 weeks of gestation, approximately 2 weeks prior to the appearance of surface IgM p