## Abstract Natural cell‐mediated cytotoxicity (NCMC), measured against a variety of tumors, is mediated by at least two sub‐populations of effector cells: natural cytotoxic (NC) and natural killer (NK). The studies described in this report show that target lysis by NC cells requires a prolonged (1
✦ LIBER ✦
Normal levels of natural cytotoxic cells against solid tumours in NK-deficient beige mice
✍ Scribed by Stutman, Osias; Cuttito, Michael J.
- Book ID
- 109722397
- Publisher
- Nature Publishing Group
- Year
- 1981
- Tongue
- English
- Weight
- 511 KB
- Volume
- 290
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/290254a0
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We have previously shown that anti-Ly-6C monoclonal antibody (MAb) 2B6-F2 identifies a subset of (CBA % C57BL/6)FI splenic NK-I. I + natural T (NT) cells which kill the NK-sensitive YAC-I target in vitro. Furthermore, these Ly-6C+ cells are responsible for 4650% of in vitro YAC-I killing in all mous