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Normal and Rearranged PAX3 Expression in Human Rhabdomyosarcoma

โœ Scribed by Emanuela Frascella; Luisa Toffolatti; Angelo Rosolen

Book ID
114136374
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
194 KB
Volume
102
Category
Article
ISSN
0165-4608

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## Abstract __PAX3__ and __PAX7__ encode transcription factors implicated in the pathogenesis of rhabdomyosarcoma (RMS), including alveolar RMS in which chromosomal translocations generate __PAX3โ€FKHR__ and __PAX7โ€FKHR__ fusions. Previous studies of wildโ€type PAX3 and PAX7 identified alternative sp