We conducted a prospective intervention study of screening for fragile X syndrome in the general population. Antenatal and preconceptional screening were carried out in 9459 women aged between 19 and 44 with no known family history of fragile X syndrome. 80% were tested antenatally. 134 carriers wer
Normal age of menarche in fragile X syndrome
โ Scribed by Burgess, Bronwyn ;Partington, Michael ;Turner, Gillian ;Robinson, Hazel
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 74 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0148-7299
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## Letter to in Norma To the Editor: the Editor: Fragile X Chromosome Males I found the recent report by Hecht, Jacky, and Sutherland [1982] on the Fragile X Chromosome Workshop (Jerusalem, September 198 1) particularly interesting and a good summary, it seems, of the present situation. However, I
The much-quoted prevalence figure of 1:1,000 males for fragile X syndrome is an overestimate in a mixed ethnic population. A reexamination of the individuals from whom those data were derived using molecular diagnostic techniques demonstrates a more realistic figure of 1:4,000 males.
o b s t r u c t i v e s l e e p apnea (OSA). A f t e r a s t r u ctured interview, 4 of them underwent an overnight polygraphic study. The r e s u l t s i n d i c a t e an increased r i s k f o r OSA among subjects with fra(X) ( 4 / 7 ) . In 2 of t h e s u b j e c t s polygraphic study indicated a s