## Abstract The phorbol ester, 12โ__O__โtetradecanoylphorbolโ13โacetate (TPA), is a potent inhibitor of gap junctional intercellular communication (GJIC). This inhibition requires activation of protein kinase C (PKC), but the events downstream of this kinase are not known. Since PKC can activate ex
โฆ LIBER โฆ
Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions
โ Scribed by Mollerup, Sarah; Hofgaard, Johannes P.; Braunstein, Thomas H.; Kjenseth, Ane; Leithe, Edward; Rivedal, Edgar; Holstein-Rathlou, Niels-Henrik; Nielsen, Morten Schak
- Book ID
- 124081161
- Publisher
- Informa plc
- Year
- 2011
- Tongue
- English
- Weight
- 311 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1541-9061
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The effects of extremely low frequency (ELF) magnetic ยฎeld on gap junctional intercellular communication (GJIC), protein levels, and phosphorylation of connexin43 (Cx43) were studied in NIH3T3 cells. The suppression of GJIC by 24 h, 50 Hz, 0.8 mT ELF magnetic ยฎeld, 2 h, 3 ng/ml 12-O-tetradecanoylpho