Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication
โ Scribed by Solveig Sirnes; Ane Kjenseth; Edward Leithe; Edgar Rivedal
- Book ID
- 116298314
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 394 KB
- Volume
- 382
- Category
- Article
- ISSN
- 0006-291X
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๐ SIMILAR VOLUMES
The effects of extremely low frequency (ELF) magnetic ยฎeld on gap junctional intercellular communication (GJIC), protein levels, and phosphorylation of connexin43 (Cx43) were studied in NIH3T3 cells. The suppression of GJIC by 24 h, 50 Hz, 0.8 mT ELF magnetic ยฎeld, 2 h, 3 ng/ml 12-O-tetradecanoylpho
## Abstract Many studies have correlated reductions in gap junctional intercellular communication (a) with altered cellular growth, tumor promotion, and neoplastic transformation. To test directly whether reduced GJIC affects cellular growth, GJIC was inhibited in murine BALB/c 3T3 fibroblasts by t