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Norepinephrine Concentrations in the Epicardial Transudate Reflect Early Changes in Adrenergic Activity in the Isolated Perfused Heart

โœ Scribed by Mojca Lorbar; Katarina Skalova; Arash Nabi; Eugene S Chung; Richard A Fenton; James G Dobson; Jr; Theo E Meyer


Book ID
115633077
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
120 KB
Volume
32
Category
Article
ISSN
0022-2828

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Phosphoinositide hydrolysis is elicited by alpha-adrenoceptor stimulation in the myocardium, resulting in the generation of 1,2-diacylglycerol by the direct activation of phospholipase C. However, the physiological role of 1,2-diacylglycerol accumulation in the heart has been largely unexplored. The