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Norepinephrine-induced 1,2-diacylgyycerol accumulation and change in its atty acid composition in the isolated perfused rat heart: Kenji Okumura, Yoshihisa Shirai, Junichiro Kondo, Hidekazu Hashimoto, Takayuki Ito, Tatsuo Satake. Second Department of Internal Medicine, Nagoya University School of Medicine, Nagoya, Japan


Book ID
115981421
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
97 KB
Volume
22
Category
Article
ISSN
0022-2828

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Norepinephrine-induced 1,2-diacylglycero
โœ Kenji Okumura; Yoshihisa Shirai; Junichiro Kondo; Hidekazu Hashimoto; Takayuki I ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 463 KB

Phosphoinositide hydrolysis is elicited by alpha-adrenoceptor stimulation in the myocardium, resulting in the generation of 1,2-diacylglycerol by the direct activation of phospholipase C. However, the physiological role of 1,2-diacylglycerol accumulation in the heart has been largely unexplored. The