Nontranscriptional actions of the glucocorticoid receptor
✍ Scribed by Florian P. Limbourg; James K. Liao
- Book ID
- 105796061
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 184 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0946-2716
No coin nor oath required. For personal study only.
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## Abstract Glucocorticoids (GCs) are hormones naturally released when the body perceives stress and function to return homeostatic balance within various tissues. Synthetic GCs are widely prescribed therapeutics for the treatment of numerous inflammatory disorders and cancers. The effects of GCs a
## Abstract A crucial step in the interaction of glucocorticoids with target cells is the activation step, which involves a conformational change in the cytoplasmic glucocorticoid–receptor protein complexes and facilitates their binding to the cell nucleus. Activation can be quantified by measuring