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Nonrandom Distribution of Aberrant Promoter Methylation of Cancer-Related Genes in Sporadic Breast Tumors

โœ Scribed by Parrella, P.

Book ID
121701186
Publisher
American Association for Cancer Research
Year
2004
Tongue
English
Weight
187 KB
Volume
10
Category
Article
ISSN
1078-0432

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## Abstract ## BACKGROUND. Methylationโ€mediated suppression of detoxification, DNA repair, and tumor suppressor genes has been implicated in cancer development and progression. Studies also have indicated that concordant methylation of multiple genes (methylator phenotypes), rather than a single g