𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Noninvasive temperature imaging using diffusion MRI

✍ Scribed by J. Delannoy; Ching-Nien Chen; R. Turner; R. L. Levin; D. Le Bihan

Book ID
102530683
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
392 KB
Volume
19
Category
Article
ISSN
0740-3194

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✦ Synopsis

Efficacy and safety considerations for cancer therapy with hyperthermia require accurate temperature measurements throughout the heated volume. We report the use of molecular diffusion, whose temperature dependence is well known. A dedicated hyperthermia applicator was built, combining a MRI gradient coil and a rf coil. Diffusion and derived temperature images were obtained with a 1 x 2 mm pixel size on a polyacrylamide gel phantom using a clinical 1.5-T whole body MRI system. Temperatures determined from these images using 1 cm2 regions of interest were found to be within 0.2 degrees C of those recorded from the thermocouples and fiber-optic probes placed inside the gel.

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