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Nonequilibrium Analysis Alters the Mechanistic Interpretation of Inhibition of Acetylcholinesterase by Peripheral Site Ligands †

✍ Scribed by Szegletes, Tivadar; Mallender, William D.; Rosenberry, Terrone L.


Book ID
120029183
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
182 KB
Volume
37
Category
Article
ISSN
0006-2960

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Peripheral site ligands accelerate inhib
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The rates of inhibition of mouse acetylcholinesterase (AChE; EC 3.1.1.7) by paraoxon, haloxon, DDVP and enantiomers of neutral alkyl methylphosphonyl thioates and cationic alkyl methylphosphonyl thiocholines were measured in the presence and absence of AChE peripheral site inhibitors: gallamine, d-t