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Noncovalent inhibition of the serine proteases, ?-chymotrypsin and trypsin by trifluoro(organo)borates

✍ Scribed by Smoum, Reem; Rubinstein, Abraham; Srebnik, Morris


Book ID
121256216
Publisher
Royal Society of Chemistry
Year
2005
Tongue
English
Weight
124 KB
Volume
3
Category
Article
ISSN
1477-0520

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Ξ±-Amino boronates as cyanoborane complex
✍ Amal Shibli; Reem Smoum; Israel Goldberg; Abraham Rubinstein; Morris Srebnik πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 120 KB

## Abstract The first examples of α‐amino boronate complexes stabilized by amino cyanoborane complexation were tested as trypsin and chymotrypsin inhibitors, and they showed moderate inhibition. The structure of compound **1** that contains two different boron atoms reveals that the geometry around