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Nonbinomial distributions of relative neurite outgrowth in PC-12 cells

✍ Scribed by Carl F. Blackman; Dennis E. House; Janie Page Blanchard

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
410 KB
Volume
17
Category
Article
ISSN
0197-8462

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✦ Synopsis

Previously we reported the results of a series of experimental tests using PC-12 cells to examine the biological effect of prescribed combinations of both nerve growth factor and magnetic fields. Because our assay of the PC-12 cells is based on binary classification of the cells following treatment, our data might be expected to have a binomial distribution. However, our data consistently show a smaller variability than that predicted by the binomial distribution model. In this paper, we examine some possible reasons for this reduction in variability in our results.

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