Non-receptor protein tyrosine kinases of normal tissues
โ Scribed by Ashok K. Srivastava
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 792 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0020-711X
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๐ SIMILAR VOLUMES
Haematopoiesis is controlled by a number of growth factors and cytokines, a number of which act through binding to high-affinity receptor tyrosine kinases (RTKs). Approximately 20 different RTK classes have been identified, all of which share a similar structure that includes a ligand binding extrac
The description in the past year of several novel protein tyrosine kinase inhibitors, which exhibit dramatic improvements in potency and specificity over earlier agents, will be considered a major turning point in the field. These compounds appear to have the necessary pharmacological properties to