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Non-productive binding of butyryl(thio)choline in the active site of vertebrate acetylcholinesterase

✍ Scribed by Jure Stojan


Book ID
113518217
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
257 KB
Volume
187
Category
Article
ISSN
0009-2797

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Rapid binding of a cationic active site
✍ Sylvia Tara; Adrian H. Elcock; Paul D. Kirchhoff; James M. Briggs; Zoran Radic; πŸ“‚ Article πŸ“… 1998 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 133 KB πŸ‘ 2 views

It is known that anionic surface residues play a role in the long-range electrostatic attraction between acetylcholinesterase and cationic ligands. In our current investigation, we show that anionic residues also play an important role in the behavior of the ligand within the active site gorge of ac