✦ LIBER ✦

Non-Peptide Glycoprotein IIb/IIIa Inhibitors. 17. Design and Synthesis of Orally Active, Long-Acting Non-Peptide Fibrinogen Receptor Antagonists

✍ Scribed by Askew, Benny C.; Bednar, Rodney A.; Bednar, Bohumil; Claremon, David A.; Cook, Jacquelynn J.; McIntyre, Charles J.; Hunt, Cecila A.; Gould, Robert J.; Lynch, Robert J.; Lynch,, Joseph J.; Gaul, Stanley L.; Stranieri, Maria T.; Sitko, Gary R.; Holahan, Marie A.; Glass, Joan D.; Hamill, Terrence; Gorham, Lynn M.; Prueksaritanont, Thomayant; Baldwin, John J.; Hartman, George D.

Book ID: 126067695
Publisher: American Chemical Society
Year: 1997
Tongue: English
Weight: 289 KB
Volume: 40
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm9608117

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Non-peptide glycoprotein IIb/IIIa inhibi

Non-peptide glycoprotein IIb/IIIa inhibitors. 6. Design and synthesis of rigid, centrally constrained non-peptide fibrinogen receptor antagonists

✍ B.C. Askew; C.J. McIntyre; C.A. Hunt; D.A. Claremon; R.J. Gould; R.J. Lynch; D.J 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 295 KB

Low molecular weight non-peptide inhibitors of platelet aggregation based on rigid bicyclic scaffolds are described. Consideration of the reported conformational preferences of 1-alkyl-3-carbonyl pyrroles led to the synthesis of pyrrolopiperazinone 2a which was shown to be a potent, selective antago

ChemInform Abstract: Non-Peptide Fibrino

ChemInform Abstract: Non-Peptide Fibrinogen Receptor Antagonists. Part 7. Design and Synthesis of a Potent, Orally Active Fibrinogen Receptor Antagonist.

✍ M. E. DUGGAN; A. M. NAYLOR-OLSEN; J. J. PERKINS; P. S. ANDERSON; C. T.-C. CHANG; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB

ChemInform Abstract: Nonpeptide Glycopro

ChemInform Abstract: Nonpeptide Glycoprotein IIb/IIIa Inhibitors. Part 13. Design and Synthesis of an Orally Active Pyrazolopiperazinone Nonpeptide Fibrinogen Receptor Antagonist.

✍ B. C. ASKEW; C. J. MCINTYRE; C. A. HUNT; D. A. CLAREMON; J. J. BALDWIN; P. S. AN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 29 KB 👁 1 views

Novel Non-Peptide Fibrinogen Receptor An

Novel Non-Peptide Fibrinogen Receptor Antagonists. 1. Synthesis and Glycoprotein IIb-IIIa Antagonistic Activities of 1,3,4-Trisubstituted 2-Oxopiperazine Derivatives Incorporating Side-Chain Functions of the RGDF Peptide

✍ Sugihara, Hirosada; Fukushi, Hideto; Miyawaki, Toshio; Imai, Yumi; Terashita, Ze 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 301 KB

ChemInform Abstract: Design and Synthesi

ChemInform Abstract: Design and Synthesis of a Novel Class of Highly Potent Selective and Orally Active Non-peptide Bradykinin B2 Receptor Antagonists

✍ Hiroshi Kayakiri; Yoshito Abe; Teruo Oku 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 26 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

New Orally Active Non-Peptide Fibrinogen

New Orally Active Non-Peptide Fibrinogen Receptor (GpIIb-IIIa) Antagonists: Identification of Ethyl 3-[ N -[4-[4-[Amino[(ethoxycarbonyl)imino]methyl]phenyl]- 1,3-thiazol-2-yl]- N -[1-[(ethoxycarbonyl)methyl]piperid-4-yl]amino]propionate (SR 121787) as a Potent and Long-Acting Antithrombotic Agent

✍ Badorc, Alain; Bordes, Marie-Françoise; de Cointet, Paul; Savi, Pierre; Bernat, 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 237 KB