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Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs): Past, Present, and Future

✍ Scribed by Erik De Clercq

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
285 KB
Volume
1
Category
Article
ISSN
1612-1872

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## Abstract α‐Aminoketone hydrochlorides **2a—d** were synthesized by Dakin‐West reaction from __L__‐phenylalanine and __L__‐cyclohexylalanine followed by hydrolysis in acidic medium. Treatment of **2a—d** with aqueous potassium thiocyanate afforded 1, 3‐imidazole‐2‐thiones **3a—d** which were alky