The dynamic stiffness method is extended to large amplitude free and forced vibrations of frames. When the steady state vibration is concerned, the time variable is replaced by the frequency parameter in the Fourier series sense and the governing partial differential equations are replaced by a set of ordinary differential equations in the spatial variables alone. The frequency-dependent shape functons are generated approximately for the spatial discretization. These shape functions are the exact solutions of a beam element subjected to mono-frequency excitation and constant axial force to minimize the spatial discretization errors. The system of ordinary differential equations is replaced by a system of non-linear algebraic equations with the Fourier coefficients of the nodal displacements as unknowns. The Fourier nodal coefficients are solved by the Newtonian algorithm in an incremental manner. When an approximate solution is available, an improved solution is obtained by solving a system of linear equations with the Fourier nodal increments as unknowns. The method is very suitable for parametric studies. When the excitation frequency is taken as a parameter, the free vibration response of various resonances can be obtained without actually computing the linear natural modes. For regular points along the response curves, the accuracy of the gradient matrix (Jacobian or tangential stiffness matrix) is secondary (cf. the modified Newtonian method). However, at the critical positions such as the turning points at resonances and the branching points at bifurcations, the gradient matrix becomes important. The minimum number of harmonic terms required is governed by the conditions of completeness and balanceability for predicting physically realistic response curves. The evaluations of the newly introduced mixed geometric matrices and their derivatives are given explicitly for the computation of the gradient matrix.