Over 30 years after the original description of Randle's cycle, the mechanisms by which elevated circulating non-esterified fatty acids might be causally related to glucose intolerance in Type 2 diabetes mellitus remain uncertain. This review examines the evidence that elevated plasma NEFA can inhib
Non-esterified fatty acids are related with hypofibrinolysis in type 2 diabetes mellitus
β Scribed by H.E. Brussaard; J.A. Gevers Leuven; H.M.J. Krans; P. Meijer; R. Buytenhek; C. Kluft
- Book ID
- 116118425
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 369 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0268-9499
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The mechanisms underlying insulin resistance in Type 2 (non-insulin-dependent) diabetes mellitus are not fully understood. An enhanced lipid/non-esterified fatty acid oxidation could provide an explanation. To test this hypothesis we examined the relationship between glucose and lipid metabolism in