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Non-equivalence of the carboxyl groups of glucagon in the carbodiimide-promoted reaction with nucleophiles and the role of carboxyl groups in the ability of glucagon to stimulate the adenyl cyclase of rat liver

โœ Scribed by Wheeler, Graham E.; Epand, Richard M.; Barrett, Dale


Book ID
122598956
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
583 KB
Volume
372
Category
Article
ISSN
0304-4165

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In view of controversial findings regarding the mechanism for the increased intracellular hepatic cyclic 3':5' adenosine monophosphate levels in diabetic rats, we studied the dose-response relationship of the adenylate cyclase to glucagon stimulation in severely diabetic and in diabetic, insulin-tre