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The effects of the trinitrophenylation of the amino groups of glucagon on its conformational properties and on its ability to activate rat liver adenylyl cyclase

✍ Scribed by Richard M. Epand; Graham E. Wheeler


Book ID
113124931
Publisher
Elsevier Science
Year
1975
Weight
575 KB
Volume
393
Category
Article
ISSN
0005-2795

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## Abstract The cationic local anaesthetics carbocaine and unpercaine were found to increase the fluoride‐stimulated adenylate cyclase up to a maximum level; above this maximum level further increases in drug concentration inhibited the enzyme. At concentrations where this activity was stimulated,