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Non-enzymatic asymmetric synthesis of (R)-(-)- and (S)-(+)-mevalolactone in high enantiomeric purity

✍ Scribed by Frye, Stephen V.; Eliel, Ernest L.


Book ID
126906227
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
469 KB
Volume
50
Category
Article
ISSN
0022-3263

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Aymmetric synthesis of (R) - and (S)-cit
✍ Stephen V. Frye; Ernest L. Eliel πŸ“‚ Article πŸ“… 1985 πŸ› Elsevier Science 🌐 French βš– 239 KB

Sumnary. An asymmetric synthesis of both isomers of dimethyl P-acetoxycitramalate in over 96% enantiomeric excess is described. ## Citramalic acid is a member of the 2-alkylmalic acid family and has been isolated from a variety of natural sources. Its structure was determined and a method for its