Non-disjunction in trisomy 21: study of chromosomal heteromorphisms in 110 families
✍ Scribed by MARGARETA MIKKELSEN; HANNE POULSEN; JßRGEN GRINSTED; AKSEL LANGE
- Book ID
- 115248838
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 982 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0003-4800
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
We report the prenatal exclusion of partial trisomy in a family with maternal pericentric inversion of chromosome 21 by fluorescence in situ hybridization (FISH). After determining the structural rearrangement in the mother and her affected son with 46,XY,rec(21)dup(21q)inv(21)(p11q22) resulting in
A recombinant clone was isolated containing a sequence which occurs only on human chromosome 21 and defines a two-allele restriction fragment length polymorphism showing Mendelian inheritance. Forty seven percent of the London population are heterozygous for the polymorphism. The chromosomal locatio