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Non-COX-2 targets and cancer: Expanding the molecular target repertoire of chemoprevention

โœ Scribed by Khosrow Kashfi; Basil Rigas


Book ID
113487628
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
426 KB
Volume
70
Category
Article
ISSN
0006-2952

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Evidence derived from several lines of investigation suggest that prostaglandins, metabolites of arachidonic acid, play an important role in colon cancer development. Elevated prostaglandin levels are found in colon cancers and their precursor lesions, adenomatous polyps. Agents such as aspirin and