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COX-2 as a molecular target of colon cancer chemoprevention: Promise and reality

✍ Scribed by Jasmeet Kaur; Vivek Vaish; Sankar Nath Sanyal


Book ID
119196036
Publisher
Elsevier
Year
2012
Tongue
English
Weight
315 KB
Volume
2
Category
Article
ISSN
2210-5220

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Evidence derived from several lines of investigation suggest that prostaglandins, metabolites of arachidonic acid, play an important role in colon cancer development. Elevated prostaglandin levels are found in colon cancers and their precursor lesions, adenomatous polyps. Agents such as aspirin and