Non-covalent inhibitors of rhinovirus 3C protease

✍ Scribed by Andrew Baxter; Mark Chambers; Fredrik Edfeldt; Karl Edman; Adrian Freeman; Cristian Johansson; Sarah King; Andy Morley; Jens Petersen; Phil Rawlins; Loredana Spadola; Bob Thong; Hervé Van de Poël; Nicola Williams

• Book ID: 104005173
• Publisher: Elsevier Science
• Year: 2011
• Tongue: English
• Weight: 700 KB
• Volume: 21
• Category: Article
• ISSN: 0960-894X
• DOI: 10.1016/j.bmcl.2010.11.110

✦ Synopsis

The first known non-covalent inhibitors of rhinovirus 3C protease (3CP) have been identified through fragment based screening and hit identification activities.