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Nomographic estimation of time to reach steady-state serum concentration during phenytoin therapy

โœ Scribed by S. Vozeh; F. Follath


Book ID
104810989
Publisher
Springer
Year
1980
Tongue
English
Weight
353 KB
Volume
17
Category
Article
ISSN
0031-6970

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A problem of substantial delay in reaching the steady state drug concentration in particular organ (compartment) compared to the time of reaching the steady state plasma concentration is considered. It is shown that the ratio of the terminal (V(beta)) and the steady state (V(ss)) volumes of distribu