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Nomenclature of human genes involved in ionizing radiation sensitivity

✍ Scribed by Larry H Thompson; Penny A Jeggo

Book ID
116157976
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
316 KB
Volume
337
Category
Article
ISSN
0921-8777

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## Abstract Fragile Histidine Triad (__Fhit__) gene deletion, methylation, and reduced Fhit protein expression occur in about 70% of human epithelial tumors and, in some cancers, are clearly associated with tumor progression. Specific Fhit signal pathways have not been identified, although it has b