Noggin and BMP4 co-modulate adult hippocampal neurogenesis in the APPswe/PS1ΔE9 transgenic mouse model of Alzheimer’s disease
✍ Scribed by Jun Tang; Min Song; Yanyan Wang; Xiaotang Fan; Haiwei Xu; Yun Bai
- Book ID
- 116298672
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 418 KB
- Volume
- 385
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Alterations in hippocampal cell proliferation have been identified in transgenic (tg) mouse models of Alzheimer's disease (AD); however, relatively little is known about the underlying mechanisms. Previously, we have demonstrated that endogenous level of BMP4 in the dentate gyrus (DG) a
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