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Nocardiamides A and B, Two Cyclohexapeptides from the Marine-Derived Actinomycete Nocardiopsis sp. CNX037

✍ Scribed by Wu, Zheng-Chao; Li, Sumei; Nam, Sang-Jip; Liu, Zhong; Zhang, Changsheng


Book ID
120232509
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
371 KB
Volume
76
Category
Article
ISSN
0163-3864

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✍ VΓ©ronique Ledroit; CΓ©cile Debitus; Catherine Lavaud; Georges Massiot πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 125 KB

The ethanolic extract of the sponge Jaspis sp. collected in Vanuatu showed cytotoxicity against KB tumour cells (IC 95 =10 mg/ml). A bioassay-guided fractionation led to the isolation of two new cytotoxic sphingosine derivatives, jaspine A and jaspine B. Structures were elucidated by spectroscopic m