Individuals with the 18q-syndrome have variable deletions from the long arm of chromosome 18. They also exhibit a highly variable phenotype. To correlate genotype with phenotype accurately, extensive molecular and phenotypic analyses are needed on each affected individual. As a part of this analysis
No preferential loss of paternal 19q alleles in oligodendroglial tumors
β Scribed by Christian Hartmann; Wolf Mueller; Ulrike Lass; Florian Stockhammer; Kajetan von Eckardstein; Julian Veelken; Judith Jeuken; Wolfgang Wick; Andreas von Deimling
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 81 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The molecular mechanisms underlying the genesis and progression of oligodendroglial tumors are poorly understood, since only restricted information on loss of heterozygosity from isolated cases is available. The commonest alterations appear to involve deletion of 1p and 19q, while loss
## Abstract HΓΌrthle thyroid tumors are characterized by frequent numerical chromosomal aberrations, including aneuploidy or polyploidy, losses and gains of some chromosomal regions and DNA fragmentation. In recent years, great attention has been paid to the combined analysis of morphologic and gene