Clinical, histological, and immunohistochemical features predicting 1p/19q loss of heterozygosity in oligodendroglial tumors
β Scribed by Se Hoon Kim; Hoguen Kim; Tai Seung Kim
- Publisher
- Springer-Verlag
- Year
- 2005
- Tongue
- English
- Weight
- 478 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0001-6322
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## Abstract The molecular mechanisms underlying the genesis and progression of oligodendroglial tumors are poorly understood, since only restricted information on loss of heterozygosity from isolated cases is available. The commonest alterations appear to involve deletion of 1p and 19q, while loss
## Incidence rates of Wilms' tumor (WT) markedly differ in East Asian and Caucasian children. In the present study, we examined WT1 deletions/mutations and loss of heterozygosity (LOH) on 11p and 11q in a large number of WTs and compared our findings with those from 4 series of Caucasian WTs. Inci