No germline mutations in the histone acetyltransferase geneEP300inBRCA1andBRCA2negative families with breast cancer and gastric, pancreatic, or colorectal cancer
β Scribed by Ian G Campbell, David Choong, Georgia Chenevix-Trench
- Book ID
- 120700410
- Publisher
- BioMed Central
- Year
- 2004
- Tongue
- English
- Weight
- 169 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1465-5411
- DOI
- 10.1186/bcr803
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The __CDKN2A/ARF__ genes have been associated with increased risk of malignant melanoma (MM) in families with multiple members affected by disease and in families characterized by the constellation of breast cancer and MM. The exact contribution of __CDKN2A/ARF__ to disease risk remains
## Abstract ## BACKGROUND. In previous experimental models, because of its ability to inhibit the activity of plateletβderived growth factor Ξ² receptor, imatinib decreased the interstitial fluid pressure and improved the delivery and efficacy of anticancer drugs, including fluorouracil. The object
Germline mutations within the adenomatous polyposis coli (APC) gene, a tumor suppressor gene, are responsible for most cases of familial adenomatous polyposis (FAP), an autosomal dominantly inherited predisposition to colorectal cancer. To date, more than 300 germ-line causative mutations within thi