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No germline mutations in the dimerization domain of MXI1 in prostate cancer clusters

✍ Scribed by Edwards, SM; Dearnaley, DP; Ardern-Jones, A; Hamoudi, RA; Easton, DF; Ford, D; Shearer, R; Dowe, A; Eeles, RA

Book ID
109837445
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
879 KB
Volume
76
Category
Article
ISSN
0007-0920

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## Abstract Somatic mutations in the __E‐cadherin__ (__CDH1__) gene have frequently been reported in cases with diffuse gastric and lobular breast cancers. Recently, germline mutations have been identified in families with diffuse gastric cancers. In families with hereditary prostate cancer (HPC),